Areas of Research

Environmental biochemistry and biotechnology is the main theme of research in this laboratory.  The goal of our research is to minimize the risks of pollutants and create high value products.  Topic areas include proteomics and metabolomics, biodegradation and biosynthesis, insect nutriproteomics and control, agricultural/analytical/environmental chemistry, and fate of pollutants and pesticides in the environment. 


Professional Societies and Affiliations


Selected patents and technologies

Rima, J.; Aouezova, L.; Li, Q.X. 2011. Generation of free radicals, analytical methods, bacterial disinfections, and oxidative destruction of organic chemicals using zero valent iron and other metals.  US patent 8,048,317



235.  Cho, I.K.; Chang, C.L.; Li, Q.X. 2013. Diet-induced over-expression of flightless-I protein and its relation to flight dysfunction in Mediterranean fruit fly, Ceratitis capitata. PLOS ONE (in press)

229.  Seo, J.-S.; Keum, Y.-S.; Li, Q.X.  2013. Metabolomic and proteomic insights into carbaryl catabolism by Burkholderia sp. C3 and degradation of ten N-methylcarbamates. Biodegradation, (in press) DOI 10.1007/s10532-013-9629-2

225.  Baker, M.R.; Li, Q.X. 2013. Guanidination tryptic peptides without desalting for MALDI MS analysis. Anal. Chem. 85(18):8873-8880.

218.  Wu, L.; Chen M.X.; Chen, Y.; Li, Q.X. 2013. Determination and evaluation of gas holdup time with the quadratic equation model and comparison with nonlinear equation models for isothermal gas chromatography. J. Chromatogr. A 1297:196-203

202.  Wang, D.; Atkinson, S.; Hoover-Miller A.; Shelver, W.; Li, Q.X.  2012. Organic halogenated contaminants in mother-fetus pairs of harbor seals (Phoca vitulina richardii) from Alaska, 2000-2002. J. Hazardous Materials 223-224:72-78.

197.  Wang, J.; Chen, W.F.; Li, Q.X. 2012. Rapid identification and classification of Mycobacterium spp. using whole-cell protein barcodes and selected markers with MALDI TOF MS in comparison with multigene phylogenetic analysis. Anal. Chim. Acta 716:133-137.

188.  Tittabutr, P.; Cho, I.K.; Li, Q.X. 2011. Phn and Nag-like dioxygenases metabolize polycyclic aromatic hydrocarbons in Burkholderia sp. C3. Biodegradation 22:1119-1133.

182.  Seo, J.-S.; Keum, Y.-S.; Li, Q.X. 2011. Comparative protein and metabolite profiling revealed metabolic network in response to multiple environmental contaminants in Mycobacterium aromativorans JS19b1T. J. Agric. Food Chem. 59(7):2876-2882.

175.  Wang, D.; Li, Q.X.  2010.  Application of mass spectrometry in the analysis of polybrominated diphenyl ethers.  Mass Spectrometry Reviews 29 (5):737-775.

153.  Chang, C.L.; Cho, I.K.; Li, Q.X. 2009. Insecticidal activity of basil oil, trans-anethole, estragole, and linalool to adult fruit flies of Ceratitis capitata, Bactrocera dorsalis, and Bactrocera cucurbitae.  J. Economic Entomology 102(1): 203-209.

152.  Hennessee, C.T.; Seo, J.-S.; Alvarez, A.M.; Li, Q.X. 2009. Isolation and characterization of five new polycyclic aromatic hydrocarbon-degrading species isolated from Hawaiian soils:  Mycobacterium crocinum sp. nov., Mycobacterium pallens sp. nov., Mycobacterium rutilum sp. nov., Mycobacterium rufum sp. nov., and Mycobacterium aromaticivorans sp. nov.  Int. J. Syst. Evol. Microbiol. 59(2):378-387.

122.  Lee, S.-E.; Seo, J.S.; Keum, Y.-S.; Lee, K.-J.; Li, Q.X.  2007.  Fluoranthene metabolism and associated proteins in Mycobacterium sp. JS14.  Proteomics 7(12):2059-2069.

103.  Lee, S.-E.; Li, Q.X.; Yu, J.  2006.  Proteomic responses to formic acid on Ralstonia eutropha. Proteomics 6:4259-4268.

82.  Keum, Y.-S.; Li, Q.X.  2005.  Reductive debromination of polybrominated diphenyl ethers by zero-valent Iron.  Environ. Sci. Technol39(7):2280-2286.

81.  Hou, S. et al.  2004.  Genome sequence of the deep-sea γ-Proteobacterium Idiomarina Ioihiensis reveals amino acid fermentation as source of carbon and energy.  Proc Natl Acad Sci USA101(52): 18036-18041.

75.  Keum, Y.-S.; Li, Q.X.  2004.  Copper dissociation as a mechanism of fungal laccase denaturation by humic acid.  Appl. Microbiol. Biotech. 64: 588-592.

70.  Paquin, D.; Campbell, S.; Li, Q.X.  2004.  Phytoremediation in sub-tropical Hawaii– a review of over 100 plant species.  Remediation. 14(2): 127-139.

57.  Zhu, Y.; Li, Q.X.  2002.  Movement of bromacil and hexazinone in soils of Hawaiian pineapple fields. Chemosphere. 49(6): 671-676.

51.  Chiu, Y.-W.; Li, Q.X.; Karu, A.E.  2001.  Selective binding of polychlorinated biphenyl congeners by a monoclonal antibody: analysis by kinetic exclusion fluorescence immunoassay. Anal. Chem73(22):5477-5484.

46.  Pellequer, J.L.; Zhao, B.; Kao, H.-I.; Bell, C.W.; Karu, A.E.; Li, K.; Li, Q.X.; Roberts, V.A.  2000.  Stabilization of bound polycyclic aromatic hydrocarbons by a p-cation interaction. J. Mol. Biology. 302(3):691-699.

45.  David, M.D.; Campbell, S.; Li, Q.X.  2000.  Pressurized fluid extraction of polar herbicides, and polar herbicides using in-situ derivatization.  Anal. Chem. 72(15):3665-3670.

42.  Thomas, S.D.; Li, Q.X. 2000.  Immunoaffinity chromatography for the analysis of polycyclic aromatic hydrocarbons in corals. Environ. Sci. & Technol. 34(12), 2649-2654.

29.  Guo, F.; Li, Q.X.; Alcantara-Licudine, J.P.  1999.  A simple Na4EDTA-assisted sub/supercritical fluid extraction procedure for quantitative recovery of polar analytes in soil.  Anal. Chem. 71:1309-1315.

27.  Li, K.; Chen, R.; Zhao, B.; Liu, M.; Karu A.E.; Roberts, V.A.; Li, Q.X.  1999.  Monoclonal antibody-based ELISAs for part-per-billion determination of polycyclic aromatic hydrocarbons: effects of haptens and formats on sensitivity and specificity. Anal. Chem  71(2):302-309.

15.  Li, Q.X.; Casida, J.E.  1994.  Structure-activity studies leading to potent chloride channel blockers: 5e-tert-butyl-2-[4-(substituted-ethynyl)phenyl]-1,3-dithianes.  Bioorg. & Med. Chem., 2(12):1423-1434.

5.  Li, Q.X.; Gee, S.J.; McChesney, M.M.; Hammock, B.D.; Seiber, J.N.  1989.  Comparison of an enzyme-linked immunosorbent assay and a gas chromatographic procedure for the determination of molinate residues.  Anal. Chem., 61:818-823.