University of Hawai‘i at Manoa
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Last updated on Thursday, March 23, 2017     Make updates ->

Jinzeng  Yang

Name :

Jinzeng Yang

Title :

Chair

Unit :

Administration

Address :

1955 East West Road
                    Honolulu, HI 96822

Room :

Ag Sciences Building 216B

Phone :

(808)956-6073

Fax :

(808)956-4024

E-mail :

jinzeng@hawaii.edu

Website :

http://www.hawaii.edu/dna

Specialties :

Molecular biolgy Animal biotechnology Transgenic animals Genetics Gene regulation Muscle biology Lactation physiology Mammary gland biology


Professional Prep/Appointments :


Postdoctoral fellow in Animal Biosciences and Biotechnology Laboratory, USDA-ARS, Beltsville Maryland
Ph.D.: University of Alberta
MSc : Animal Genetics, Huazhong Agricultural University
BSc : Animal Science,  Agricultural University of Hebei

Projects :


Regulation of Myostatin Gene Expression Publications 1.Yang, J, T Ratovitski, J P Brady, M B Solomon, K D Wells, R J Wall. 2001.Expression of myostatin pro domain results in muscular transgenic mice. Molecular Reproduction and Development 60: 351-61. 2.Yang, J, JJ Kennelly and VE Baracos 2000. Transcription factor Stat5 responses to prolactin, growth hormone and IGF-I in rat and bovine mammary gland explant, Journal of Animal Science 78: 3114-25.

Courses Offered:


ANSC446-Genes and Animal Biology
MBBE/ANSC 650-DNA and Genetic Analysis

Research Interests :


1. Molecular biology of animal development and metabolism
2. Skeletal muscle and diabetes prevention
3. Animal genetics Program in beef cattle  

Selected Publications :


  1. Qian L, Tang M, Yang J, et al. Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs. Scientific Reports. 2015; 5:14435. doi:10.1038/srep14435.
  2. Zhou Y, Yang J, Huang J, Li T, Xu D, Zuo B, Hou L, Wu W, Zhang L, Xia X, Ma Z, Ren Z, Xiong Y. 2014. The formation of brown adipose tissue induced by transgenic over-expression of PPARγ2. Biochem Biophys Res Commun. 446:959-964.
  3. Yang J, 2014. Enhanced skeletal muscle for effective glucose homeostasis.

    Progress in Molecular Biology and Translational Science 121:133-63.

  4. Yang J, 2013. Roles of myostatin propeptide in promoting skeletal muscle growth and metabolism (Book Chapter. In “Skeletal Muscle: Physiology, Classification and Disease” edited by M. Willems, Nova Sci. Publisher. Page 207-218.
  5. Wu L, Yang J. 2012. Identifications of captive and wild tilapia species existing in Hawaii by mitochondrial DNA control region sequence. PLoS One. 7(12):e51731.
  6. Li Z, Zeng F, Mitchell AD, Kim YS, Wu Z, Yang J*. 2011. Transgenic overexpression of bone morphogenetic protein 11 propeptide in skeleton enhances bone formation. Biochem Biophys Res Commun. 416: 289-92.
  7. Pan G and Yang J*. 2010. Analysis of Microsatellite DNA Markers Reveals no Genetic Differentiation between Wild and Hatchery Populations of Pacific Threadfin in Hawaii. International Journal of Biological Science 6:827-833
  8. Li Z, Kawasumi M, Zhao B, Moisyadi S, Yang J*. 2010. Transgenic Over-expression of Growth Differentiation Factor 11 Propeptide in Skeleton Results in Transformation of the Seventh Cervical Vertebra into a Thoracic Vertebra Molecular Reproduction and Development 77: 990-997.
  9. Kim KH, Kim YS, Yang J. 2010. The muscle-hypertrophic effects of clenbuterol is additive to the hypertrophic effect of myostatin suppression. Muscle & Nerve 43:700-707
  10. Wang H, Iwai TJ, Zhao B, Lee CS, Yang J*.  2010. Identification of microsatellite DNA markers for Pacific threadfin parentage assignment. J. World Aquaculture Society, 41: 640-647. 
  11. Pan G  and Yang J. 2010. Analysis of Microsatellite DNA Markers Reveals no Genetic Differentiation between Wild and Hatchery Populations of Pacific Threadfin in Hawaii. International Journal of Biological Science 6:827-833
  12. Zhao B, Li EJ, Wall RJ, Yang J*. 2009. Coordinated patterns of gene expression for adult muscle build-up in transgenic mice expressing myostatin propeptide. BMC Genomics. 10:305-315.
  13. Yang, J, T Ratovitski, J P Brady, M B Solomon, K D Wells, R J Wall. 2001.Expression of myostatin pro domain results in muscular transgenic mice. Molecular Reproduction and Development 60: 351-61.
  14. Laoong-u-thai Y, Zhao B, Phongdara A, Ako H, Yang J. 2009. Identifications of SUMO-1 cDNA and its expression patterns in Pacific white shrimp Litopeanaeus vannamei. Int J Biol Sci. 5:205-14.
  15. Li Z, B. Cao, Zhao B, Yang X, Fan MZ, Yang J. 2009. Decreased expression of calpain and calpastatin mRNA during development are highly correlated with muscle protein accumulation in neonatal pigs. Comp. Biochem. Physiol. A: Mol. Integrat. Physiol. 152:498-503.
  16. Suzuki,ST,  Zhao B, Yang J. 2008. Enhanced muscle by myostatin propeptide increases adipose tissue adiponectin, PPAR-α and PPAR- γ expressions. Biochem. Biophys. Res. Commun. 369: 767-73.
  17. Yang J, Ferreira R, DuPonte MW, Fukumoto GK, Zhao B. 2008. Growth performances of F1 Angus Plus calves grazing on pasture in Hawaii’s tropical climate. Tropical Animal Health and Production. 40: 1438-1444.   
  18. Wu Z, Li Z, Yang J. 2008. Transient transgene transmission to piglets by intrauterine insemination of spermatozoa incubated with DNA fragments. Molecular Reproduction and Development 75: 26-32.
  19. Bobbili NK, Kim YS, Dunn MA, Yang J, Ong A. 2008. Effects of maternal immunisation against myostatin on post-natal growth and skeletal muscle mass of offspring in mice. Food and Agricultural Immunology. 19: 93-106.
  20. Cesar J and Yang J. 2007. Expression patterns of ubiquitin, heat shock protein 70, alpha-actin and β-actin over the molt cycle in the abdominal muscle of marine shrimp Litopenaeus vannamei. Molecular Reproduction and Development 74: 554-559.
  21. Yang J, Zhao B. 2006. Postnatal expression of myostatin propeptide cDNA maintained high muscle growth and normal adipose tissue mass in transgenic mice fed a high-fat diet. Molecular Reproduction and Development 73:462-469.
  22. Cesar J, Zhao B,  Malecha S,  Ako H,  Yang J. 2006. Morphological and biochemical changes in the muscle of the marine shrimp litopenaeus vannamei during the molt cycle.  Aquaculture 261:688 -694.
  23. Zhao B, Wall RJ, Yang J. 2005. Transgenic expression of myostatin propeptide prevents diet-induced obesity and insulin resistance. Biochemical and Biophysical Research Communications. 337:248-255.
  24. Yang J, Zhao B, Baracos VE, Kennelly JJ. 2005. Effects of bovine somatotropin on beta-casein mRNA levels in mammary tissue of lactating cows. Journal of Dairy Science. 88: 2806-2812.
  25. Yang J, Ratovitski T, Brady JP, Solomon MB, Wells KD, Wall RJ. 2001. Expression of Myostatin Pro Domain Results in Muscular Transgenic Mice. Molecular Reproduction and Development 60: 351-361.
  26. Yang, J, JJ Kennelly and VE Baracos 2000. Transcription factor Stat5 responses to prolactin, growth hormone and IGF-I in rat and bovine mammary gland explant, Journal of Animal Science 78: 3114-25.


Languages :


English and Chinese