College of Tropical Agriculture and Human Resources
overview button
botany button
natural habitats button
horticulture and production button
harvesting and processing button
pest and diseases button
health-related research
review articles button
2002 conference button
bibliography button
new button
search button
Health-Related Research

Chemical Constituents of Noni (Morinda citrifolia)
Following is a partial list of chemical constituents isolated from noni, and their proposed or documented medicinal qualities or cultural significance. The table was assembled from the literature presented in the “Noni Bibliography” on this web site. There are reportedly numerous other compounds isolated from the noni plant that may have significant biological activity and are currently under investigation.
Noni Plant organ(s) Compound(s) Proposed or documented effects of compounds Discussion & Notes
FRUIT and FRUIT JUICE Alkaloids (xeronine) In theory, xeronine enhances enzyme activity and protein structure *According to some authorities, the existence and the proposed effects of the so-called alkaloid, xeronine, and/or the compound, pre-xeronine, have not been substantiated.
  Polysaccharides (glucuronic acid; galactose; arabinose; rhamose; glycosides; trisaccharide fatty acid ester) Immuno-stimulatory; immuno-modulatory; anti-bacterial; anti-tumor; anti-cancer. A promising area for research and a highly beneficial set of compounds.
  Scopoletin Dilates vasculature & lowers blood pressure; anti-bacterial & anti-fungal; anti-inflammatory; analgesic; histamine-inhibiting; arthritic conditions; allergies; sleep disorders; migraine headaches; depression; Alzheimer’s disease. Potentially wide applications.
  Vitamins and Minerals: magnesium; iron; potassium; selenium; zinc; copper; sulfur; ascorbic acid (vitamin C). The positive medical effects of the vitamins and minerals in noni juice are well documented. For any questions or medical and health concerns, consult a physician or dietician. Noni juice is an excellent source of vitamin C.
FOLIAGE & CELL SUSPENSIONS Anthraquinones (damnacanthal) Antiseptic & antibacterial effects in digestive tract (Staphylococcus, Shingela, Salmonella). Internal application.
  Glycosides (flavonol glycoside; iridoid glycoside, “citrifolinoside”) Anti-cancer effects: (DPPH free radical scavenging activity; inhibition of UVB-induced Activator Protein-1 activity in cell cultures. Discovery reported in 2001.
ROOTS Anthraquinones (damnacanthal) Inhibits formation of lung carcinoma in mice. Research from University of Hawai’i at Manoa
  Morindin and Morindone Dyes, yellow and red colorants used for tapa cloth; anti-bacterial. Culturally significant.
*References: please refer to “Medical Research and Noni Chemistry” section of the Noni Bibliography on this web site and the review article by Dr. Will McClatchey.

Last Updated on December 7, 2006